High content analysis tools

 

Boutter et.al. paper supplementary

List of selected features

Every feature value was measured both on the detected cell and the surrounding region using CellProfiler. For detailed explanation see [1] and [2].

 

Intensity features

  • Integrated Intensity
  • Mean Intensity
  • Std Intensity
  • Min Intensity
  • Max Intensity
  • IntegratedIntensity Edge
  • MeanIntensity Edge
  • StdIntensity Edge
  • MinIntensity Edge
  • MaxIntensity Edge
  • Mass Displacement

Texture (Haralick) features

  • Angular second moment
  • Contrast
  • Correlation
  • Variance
  • Inverse difference moment
  • Sum average
  • Sum variance
  • Sum entropy
  • Entropy
  • Difference variance
  • Difference entropy
  • Info meas 1-2
  • Gabor X&Y

 

References

[1] Carpenter, A. E.; Jones, T. R.; Lamprecht, M. R.; Clarke, C.; Kang, I. H.; Friman, O.; Guertin, D. A.; Chang, J. H.; Lindquist, R. A.; Moffat, J.; et al. CellProfiler: Image Analysis Software for Identifying and Quantifying Cell Phenotypes. Genome Biol. 2006, 7(10), R100.

[2] Haralick. Textural Features for Image Classification. IEEE Transaction on Systems Man, Cybernetics, 1973

 

 

 

 

 

 

 

 

 

 

 

 

 

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